Hypoplastic Left Heart Syndrome is seen one of the most complex heart defects in newborns and remains probably the most challenging to of all congenital of all congenital heart defects. In a child with HLHS all on the left side on the left side of the heart is still underdeveloped. This results in the left side of the heart is completely unable circulation through the circulation through the organs of the body to support. – The most common treatment for HLHS is ‘staged reconstruction ‘in which a series of operations, usually three, are performed to reconfigure the child cardiovascular system as efficient as possible despite the lack of an adequate left ventricle. Current management in major pediatric heart centers in survival rate of 75 % or better managed..
A possible ecological factor and is by Dr. Eghtesady and his colleagues examined recurring is maternal exposure to the common agent strep throat, which is also responsible known for the devastating condition such as rheumatic heart disease, numerous studies have shown that an immune reaction. To streptomycin in rheumatic heart disease, the left side cause injury to the left side of the heart the the page in HLHS. Eghtesady preliminary study suggests that many mothers whose newborns had left-sided heart injury a significant history of problems related to strep throat had.As part of their earlier work had been is generated the Montell group of mutated flies which faults into the border regions of cellular migration to show. That study identified five of genes mutating into these flies and gives the researchers a baseline for more more detailed analysis how those in in in cell migration. Wang commenced to investigate some of these genes is further subdivided her function. The researchers hope perform well more whole genomic analyzes to identify genes interact with interact with those already known to be a part in cell migration and metastasis. ###The research Cell Cell Migration Consortium.
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