Employee at Yale, with the technology AQUA? to quantitatively measure protein expression in melanoma tissue microarrays, also found an overexpression of the protein. According to the study, these data suggest, in Boston MITF a class of line survival or line addiction ‘ oncogenes to both tissue – specific development and tumor progression required represents, said David Rimm, an author of the study and associate professor in the the Department of Pathology at the Yale School of Medicine.
The researchers found that the MITF master regulator is the target gene amplification in melanoma. MITF amplification was also more frequent in metastasis and with a reduced with a reduced overall survival of the patients.Xiao be his team are findings and future research directions in the Celebrity Gordon Research Conference the directed mutagenesis show at Oxford in this summer.